A biomedical engineering minor is open to students in all majors. It is designed to
provide non-BME students a solid foundation in biomedical engineering and an in-depth
training in professional skills in addition to their study in their primary major.
This training will empower students to develop new professional skills, leading to
more job opportunities.
The minor curriculum consists of three core courses and three electives for a total
of 18 credit hours. Students who are interested in this program must register by completing a BME minor registration form and submitting it to the Biomedical Engineering Department office. The BME minor program director will review it and approve the student鈥檚 declaration
of the minor. Students enrolled in the minor must maintain an overall GPA of 3.0 or
above. All courses taken to satisfy the BME minor
requirements must be taken as a letter grade.
Core courses (minimum 9 credit hours)
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BME 201 - Intro to Biomedical Eng
"This is an introductory course for biomedical engineering undergraduate students.
It covers topics such as recombinant DNA technologies, cell and tissue engineering,
stem cell and organ regeneration, 3D tissue and organ printing, the design of tissue
engineered products, biomaterial and tissue scaffolding, drug delivery, biomechanics,
bioinstrumentation, engineering of immunity, and bio and medical imaging, etc. The
application of nano-biotechnology in developing clinical products such as tissue engineered
products, drug delivery systems, etc. will be emphasized in the course. Prerequisite:
PHYS 131, Math 225. Co-requisite BIOL 113. Fall semester. 3 credit hours.
Levels: Undergraduate
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BME 203 - Biomed Modeling Numerical Meth
This is an introductory course for biomedical engineering undergraduates. It covers
topics such as error propagation, linear and non-linear models of biological behavior,
iterative solutions to systems of equations, finite difference methods, numerical
interpolation and integration, dynamical biomedical systems modeling, ordinary and
partial differential equations. Prerequisite: Math 226 , BME 201 . Spring semester.
3 credit hours.
Levels: Undergraduate
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BME 213 - Biomolecular Engineering
This course introduces engineering principles applied to processes involving recombinant
protein production. It illustrates the development of tools and technologies of molecular
biology and their application in protein engineering. The engineering aspects of quantitative
bioprocess analysis is particularly emphasized in this course. Topics include bioprocessing,
recombinant DNA technologies, material balances, mass transfer, bioreaction, and bioreactor
engineering.
Prerequisites: BME 201, CHEM 111, BIOL 113, MATH 324 or 371. 3 credit hours.
Spring semester.
Levels: Undergraduate
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BME 303 - Bio-fluid Mechanics
This course is a core course for biomedical engineering undergraduates. This course
introduces students to basic understanding and analysis of macro and microscopic phenomena
of fluid mechanics with special emphasis on applications of fluid mechanics to biomedical
systems. Fluid flows in biomedical systems mediate the transport of energy, mass and
momentum, which is essential to the function of living systems. Perturbations in these
processes often underlie disease development. Course topics expand from from the basic
properties of fluids, the physics of fluid flow, to cardiovascular fluid mechanics,
pulmonary gas exchange, and renal blood flow and sodium transport. Prerequisites: PHYS 131 , MATH
227, BME 318. 3 credit hours. Spring semester.
Levels: Undergraduate
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BME 313 - Biomaterials
This is an introductory biomaterials course for biomedical engineering undergraduate
students. The course covers the primary biomaterial types including metals, ceramics,
polymers, carbons, and composites as well as their uses in biomedical devices and
implants. The application of these materials in tissue engineering, drug delivery,
orthopedic implants, ophthalmologic devices, and cardiovascular devices will be particularly
discussed. The biological response to implanted materials is emphasized in the course
in terms of inflammation, immunity, infection, and toxicity. The regulatory biomedical
device approval process is introduced as a natural extension of biocompatibility testing.
Prerequisites: BIOL 113, CHEM 231 , BME 213
Fall semester. 3 credit hours.
Levels: Undergraduate
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BME 318 - Biomechanics
This course introduces students to concepts of engineering mechanics required to
understand the structure and movement of biological systems. This course will deal
primarily with explaining biomechanics from a continuum mechanics perspective. The course covers topics such as concepts of tensorial stress and strain,
constitutive equations, mechanical properties of biosolid materials, viscoelasticity,
torsion, and bending. The course also introduces topics specifically relevant to biological
materials such as anisotropy, heterogeneity and failure mechanics. In addition to
exploring fundamental engineering mechanics, this course will also enable students
to apply these engineering principles to relevant real world biomedical problems.
Prerequisites: PHYS 131 , MATH 227.
Fall semester. 3 credit hours.
Levels: Undergraduate
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BME 324 - Biomedical Instruments
This is an introductory course for biomedical engineering undergraduates. It covers
topics such as bioelectric signals, biomedical electronics, biomedical electrodes
and sensors, instrumentation in diagnostic cardiology, extracorporeal devices, Instrumentation
in blood circulation, and new technologies and advances in medical instrumentation.
The course includes weekly labs to demonstrate the principles learned in class. The
labs cover biosignal recording (finger pulse, ECG, EEG, and EMG), nerve conduction
study, Wheatstone bridge circuit, and Op-Amp and filter circuits. Prerequisites: BME
201, BME 203, BME 213, PHYS 132. Fall semester. 4 credit hours.
Levels: Undergraduate
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BME 340 - Bioinformatics & Biostatistics
This course introduces students to Biostatistics and Bioinformatics. The course
covers the basic methods utilized to statistically analyze and present biological
data using R programming language. Current tools, databases, and technologies in bioinformatics
are discussed in this course. Topics include random variables and probability distributions,
hypothesis testing and statistical inference, ANOVA, sequence alignment and database
searching, DNA sequencing, and BLAST.
Prerequisites: BIOL 113 , BME 203 . Spring Semester. 3 credit hours.
Levels: Undergraduate
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BME 351 - Biomedical Engineering Lab
This is a lab-based, complimentary course for biomedical engineering junior undergraduate
students pertaining to principles of biomaterials, biomechanics, biomolecular engineering,
and biofluidics. This lab course is designed to cover biomaterials, biomechanics,
biomolecular engineering, and biofluidic mechanics in order to formulate and solve
problems in biomedical systems including experimental design, performance, and analysis.
Course fee applies. Refer to the Schedule of Classes. Prerequisites: BME 213 , BME
324, BME 318 .
Co-requisite: BME 303. Spring Semester. 1 credit hour.
Levels: Undergraduate
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BME 413 - Biomedical Transport Phenomena
This course combines both fundamental engineering with physics and life sciences
principles to provide focused coverage of key momentum and mass transport phenomena
relevant to biomedical engineering. This course covers topics including thermodynamics,
the physical principles of body fluids and cell membranes, molecular motors, cellular
mechanics, solute and oxygen transport, pharmokinetic transport and extracorporeal
devices such as blood oxygenators, hemodialysis and enzyme reactors. The course will
also explore the design of modern day bioartifical organs. The goal of the lecture
course is to emphasize the chemical and physical transport phenomena essential for
biological life and the design and development of contemporary biomedical devices
relevant to transport. Prerequisites: BME 303, BME 318, BME 330.
Fall semester. 3 credit hours.
Levels: Undergraduate
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BME 432 - Ethics in Engineering
Our goal on offering this course is to bring contextual understanding of the fundamental
relationships between professional responsibility and damage wrought by natural disasters.
We have chosen Hurricane Katrina, as it is still very relevant today yet sufficient
time has passed such that careful analysis of the storm and its aftermath is underway.
While the course focuses upon the profession of engineering, it is equally as relevant
for students entering a vast array of professions. We seek to move students understanding
of the tragic occurrence of disasters such as Hurricane Katrina from a purely analytical one to an understanding
that can begin to lead to empathy and ultimately compassion. For it is our belief
that such compassion can and will lead to more enlightened, courageous future leaders
willing to act in the face of imminent threat whatever professions our students decide
to pursue. Co-requisite: BME 450. Fall semester. 3 credit hours.
Levels: Undergraduate
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BME 433 - Human Physiology
An introduction to the major organ systems of the body with an emphasis on regulatory
processes and interactions with other systems. The course provides students with a
basic understanding of the prevalent theories of physiology and pathophysiology and
the application of these theories to health concerns relevant to biomedical engineering.
Prerequisites: BIOL 113 , CHEM 231 . Fall semester. 3 credit hours.
Levels: Undergraduate
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BME 450 - Biomedical Eng Design I
This is the first part of the culminating design experience for biomedical engineering
undergraduate students. Students are challenged to design, and deliver design solutions
to open ended problems of interest to the biomedical engineering community. This first
course takes the students from problem definition to a finished preliminary design. Course fee applies. Prerequisite: Senior standing in
Biomedical Engineering BME 318, BME 351. Co-requisite: BME 413. Fall Semester. 3 credit
hours.
Levels: Undergraduate
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BME 451 - Biomedical Eng Design II
This is the second part of the culminating design experience for biomedical engineering
undergraduate students. Students are challenged to design, and deliver design solutions
to open ended problems of interest to the biomedical engineering community. This second
course takes the students from a finished preliminary design to implementation, evaluation,
redesign and a finished project including a formal technical report and oral presentation.
Course fee applies. Prerequisite: BME 450 . Spring Semester. 3 credit hours.
Levels: Undergraduate
Elective courses (minimum 9 credit hours)
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BME 420 - Biomed Devices & Diagnostics
This is an advanced course for biomedical engineering undergraduates and beginning
graduate students. The course covers studies of significant medical devices with a
discussion of appropriate physiology, system design, biocompatibility issues, and
clinical need. Details on technological function and administration of diagnosis and/or
therapy are covered along with standard requirements from organizations. Prerequisites:
BME 324 and BME 351, Fall semester, Lecture 3 credit hours per week.
Levels: Undergraduate
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BME 424 - Bioimaging
This is an introduction to biomedical imaging systems for biomedical engineering
senior undergraduate students and graduate students. The course covers biomedical
imaging with an emphasis on fundamental principles and applications of each modern
imaging modality including X-ray radiography, computed tomography (CT), nuclear medicine
(SPECT and PET), magnetic resonance imaging (MRI), and ultrasound. Lecture 3 hours
per week. Prerequisite: BME 324. 3 Credit hours. Spring semester.
Levels: Undergraduate
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BME 428 - Biophotonics&Image Processing
Description: It covers advanced topics in biophotonics, including physical optics,
tissue optics, and digital image acquisition and formats. Additional topics include
modern optical imaging technologies, Raman spectroscopy, super-resolution microscopy,
optogenetics, photoacoustic tomography, photodynamic therapy, and live-cell imaging
microscopy. The course will also cover fundamentals and methods for digital image
processing, featuring applications in biological and medical diagnosis. Students are
required to have basic skills in MATLAB programming. In addition, the course will
include a discussion of bias and unfairness that unintentionally generated in imaging
processing and discuss best practices on how to identify and overcome them.
3 credits.
Spring semester.
Prerequisites: BME 324 and BME 351
Levels: Undergraduate
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BME 442 - Nanotechnology & Drug Delivery
The course introduces basics concepts of nanobiotechnologies, including mathematical
description of controlled release, and targeted and passive drug delivery. Different
types of drug delivery nanotechnologies, including lipid-, polymer-, hydrogel-, and
virus-based delivery systems and their application in disease treatments are also
covered in this course. Undergraduate Prerequisite: BME213, MATH 324 .
Fall semester. 3 credit hours.
Levels: Undergraduate
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BME 443 - Quantitative Instr Bioanalysis
This is an advanced, elective course for biomedical engineering undergraduates
and beginning graduate students. Quantitative instrumental bioanalysis is an overview
course including various instrumental bioanalysis principles and methods commonly
used in the pharmaceutical industries and biomedical research. The current biotechnologies
based on these instrumental analyses are discussed along with the strategy of the
quality control in the healthcare industry. The course focuses on the principles and
practical application of the analytical instruments used for quantitative analysis
in medicine, healthcare, and biomedical research.
Prerequisite: BME 324 and 351. Spring Semester. 3 credit hours.
Levels: Undergraduate
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BME 453 - Biomed Data Man & Reg Science
This is a lecture-based course for biomedical engineering senior undergraduate
students and graduate students interested in big data management as it relates to
healthcare systems. Some of the topics in this course include biomedical data acquisition,
data mining methodologies, information processing, healthcare systems, and FDA regulations.
Students will use various computational tools to manipulate large data sets as part
of homework assignments and projects. Prerequisite: BME 340. Spring semester. 3 credit hours.
Levels: Undergraduate
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BME 463 - Bioprocess Engineering
This course introduces engineering concepts for biological conversion of raw materials
to pharmaceuticals, fuels, and chemicals. Includes enzyme kinetics and technology;
bioreactor kinetics; design, analysis, control, and sterilization of bioreactors and
fermenters; genetic engineering of organisms to generate commercially-relevant products;
and downstream product processing. Prerequisites: CHEM 231 , BME 213. Spring Semester.
3 credit hours.
Levels: Undergraduate
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BME 470 - Advanced Bioinformatics
This course is a continuation of Biostatistics and Bioinformatics (BME 340). The
course covers advanced topics in modern bioinformatics. Topics include, advanced database
searching and sequence alignment, molecular phylogeny and evolution, analysis of next-generation
sequence data, microarray, data analysis, protein analysis and proteomics, and personalized
medicine and drug design. The course includes computer labs as part of the lectures
that cover computational tools used to analyze genomic and proteomic data. Prerequisites:
BME 340. Fall Semester. 3 credit hours.
Levels: Undergraduate
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BME 472 - Expermntal Design & Stat Anyls
This is an advanced course for biomedical engineering senior undergraduates. It
covers topics such as experimental design and hypothesis testing, ANOVA, MANOVA, linear
and multiple regression, generalized linear modeling, principal component analysis,
clustering, sampling methods, and bioinformatics. Prerequisites: BME203 , MATH
323 . 3 credits.
Fall semester. 3 credit hours.
Levels: Undergraduate
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BME 473 - Adv Biomat & Biocompatibility
This is an advanced course for biomedical engineering senior undergraduate students.
The course covers topics such as material mechanical and surface properties, material
degradation mechanisms, and microparticles and nanoparticles. These topics are discussed
with a focus on cardiovascular, orthopedic, ophthalmological and dental. Additionally,
the biological response to materials is covered in-depth including inflammation, thrombosis,
and immunity. Prerequisite: BME 313. Spring semester. 3 credit hours.
Levels: Undergraduate
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BME 483 - Tissue Engineering
This course introduces Tissue Engineering approaches at genetic and molecular,
cellular, tissue, and organ levels. Topics include cell and tissue in vitro expansion,
tissue organization, signaling molecules, stem cell and stem cell differentiation,
organ regeneration, biomaterial and matrix for tissue engineering, bioreactor design
for cell and tissue culture, clinical implementation of tissue engineered products,
and tissue-engineered devices. Prerequisites: BME 313, BME 201, BIOL113.
Co-requisite: BME 433. Fall semester. 3 credit hours.
Levels: Undergraduate
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BME 484 - Al in Biomed Engineering
This is a lecture-based course for biomedical engineering students interested in
learning and applying artificial intelligence (AI) approaches to real-world biomedical
problems. The course focuses on principles of a number of AI and machine learning
tools such as clustering, regression, decision trees, random forests and neural networks
and their applications in various areas of biomedical engineering, such as biomedical
data analysis, disease diagnosis, clinical risk stratification, disease progression
modeling, patient outcome prediction, and phenotype and biomarker discovery. Students
will use various computational tools to manipulate large data sets as part of homework
assignments and projects. Prerequisites: MATH 227 (Cal II), BME 203 and BME 340 or
instructor approval. Fall semester. 3 credit hours.
Levels: Undergraduate